Although both conditions cause swelling, they differ in several key aspects:

• Cause: fat distribution disorder in lipedema, impaired lymphatic drainage in lymphedema

• Distribution: symmetrical in lipedema, often asymmetrical in lymphedema

• Pain: lipedema is usually painful, lymphedema is often less painful or painless

• Involvement of feet/hands: typically spared in lipedema, commonly affected in lymphedema

• Response to elevation: little to no improvement in lipedema, often noticeable improvement in lymphedema

An accurate diagnosis is made through a professional clinical assessment and is essential for choosing the appropriate therapy.

Depending on the condition, different symptoms may predominate:

In lipedema:

• Pain during pressure or physical strain

• A feeling of heaviness in the legs or arms

• Symptoms that worsen throughout the day

• Emotional distress due to visible physical changes

In lymphedema:

• Visible swelling

• A sensation of tightness

• Reduced mobility

• Skin changes in long-standing cases

Both conditions may occur simultaneously, which can further complicate treatment.

Therapy Components for Lipedema and Lymphedema

Conservative Therapy
In both conditions, the foundation of treatment is complex decongestive therapy, tailored to the specific diagnosis. 

Core components include:

• Manual lymphatic drainage

• Compression therapy

• Exercise therapy

• Skin care

In lipedema, the primary focus is on pain relief and functional improvement. In lymphedema, treatment aims to reduce swelling and prevent complications.

Movement and Active Therapy
Regular, joint-friendly physical activity supports lymphatic flow, enhances the muscle pump mechanism, and contributes to tissue stabilization.

Complementary Measures
Depending on individual needs, additional measures such as patient education, nutritional counseling, psychosocial support, or further medical interventions may be beneficial.

Lipedema and lymphedema are distinct chronic conditions that require individualized, professionally guided treatment. A clear diagnosis is essential in order to address symptoms effectively and achieve long-term relief.

With a combination of manual therapy, compression, movement, and personalized care, symptoms can often be significantly improved and quality of life sustainably enhanced.